Archives of Gerontology and Geriatrics
Volume 54, Issue 1 , Pages 9-15 , January 2012

Association between inflammatory-related disease burden and frailty: Results from the Women's Health and Aging Studies (WHAS) I and II

  • Sandy S. Chang

      Affiliations

    • Section of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, P.O. Box 208025, 333 Cedar St., New Haven, CT 06520-8025, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 203 737 4814; fax: +1 203 688 4209.
  • ,
  • Carlos O. Weiss

      Affiliations

    • Division of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine, John R. Burton Pavillion, 5505 Hopkins Bayview Circle, Baltimore, MD 21224, USA
  • ,
  • Qian-Li Xue

      Affiliations

    • Division of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine, John R. Burton Pavillion, 5505 Hopkins Bayview Circle, Baltimore, MD 21224, USA
  • ,
  • Linda P. Fried

      Affiliations

    • Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, R1048, New York, NY 10048, USA

Received 13 February 2011 ,Revised 16 May 2011 ,Accepted 17 May 2011.

  • Image Result

    Predicted probabilities and 95%CIs of frailty by the total inflammatory disease count (0, 1, 2, and ≥3). The predicted values were derived from PRs of frailty, adjusted for age, race, education, and s

    Predicted probabilities and 95%CIs of frailty by the total inflammatory disease count (0, 1, 2, and ≥3). The predicted values were derived from PRs of frailty, adjusted for age, race, education, and smoking.

  • Image Result
    Prevalence percentages of the ten most common inflammatory disease combinations associated with frailty from the WHAS I and II, according to frailty status. The disease combinations are listed in orde

    Prevalence percentages of the ten most common inflammatory disease combinations associated with frailty from the WHAS I and II, according to frailty status. The disease combinations are listed in order from left to right based upon their highest to lowest frequencies in the frail population. Inflammatory disease combinations with prevalence percentages less than 5.0% among frail women are not displayed. Abbreviations: Ck=chronic kidney disease; D=depressive symptoms; Cv=cardiovascular disease; Pu=pulmonary disease; A=anemia; Pa=peripheral artery disease.

PII: S0167-4943(11)00130-0

doi: 10.1016/j.archger.2011.05.020

Archives of Gerontology and Geriatrics
Volume 54, Issue 1 , Pages 9-15 , January 2012